Investigation of Few-Layer Graphene Ubiquitin Interactions Optical Spectroscopy #WorldResearchAwards
Introduction Understanding protein–nanoparticle interactions is a rapidly advancing area of research due to its profound implications in biomedicine , biosensing , and nanotechnology . Among various nanomaterials, few-layer graphene (FLG) has attracted significant attention because of its unique physicochemical properties , high surface area, and biocompatibility . Proteins interacting with nanomaterials often undergo conformational changes that can alter their biological function. Ubiquitin , a small yet functionally critical protein involved in protein degradation , signaling, and cellular regulation , serves as an excellent model to study these interactions. Investigating FLG–ubiquitin complexes provides valuable molecular-level insight into how nanomaterials can be safely integrated into biological systems without compromising protein structure or function. Rationale for Studying FLG–Ubiquitin Interactions Ubiquitin’s compact structure, well-defined secondary elements, and biol...